PROTAC MLKL Degrader-2
Ref. TM-T200218
10mg | To inquire | ||
50mg | To inquire |
Product Information
PROTAC MLKL Degrader-2, a PROTAC that targets MLKL (Mixed Lineage Kinase), incorporates the PROTAC target protein ligand, E3 ligase ligand Thalidomide, and PROTAC Linker N-Methylpiperazine. The conjugate of the E3 ubiquitin ligase ligand and Linker is Thalidomide-N-Methylpiperazine. This compound exhibits antinecroptotic activity in human cell lines and effectively degrades MLKL in the HT-29 xenograft mouse model.
Chemical properties
Technical inquiry about: TM-T200218 PROTAC MLKL Degrader-2
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