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Cernuumolide J
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Cernuumolide J

CAS: 2019163-02-9

Ref. TM-T200239

10mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Friday 14 Feb 2025

Product Information

Name:
Cernuumolide J
Synonyms:
  • TMJ-105
Description:

Cernuumolide J (TMJ-105) functions as a JAK2/STAT3 inhibitor and exhibits potent activity against HEL leukemia cells by inhibiting their growth in both time-dependent and concentration-dependent manners, with an IC 50 value of 1.79 μM. This compound effectively induces G2/M phase arrest and apoptosis by downregulating the phosphorylation of JAK2, STAT3, and Erk, while simultaneously upregulating the phosphorylation of JNK and p38 MAPK. Cernuumolide J holds potential for research applications in anti-cancer therapy.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
450.52
Formula:
C24H34O8
Color/Form:
Liquid
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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