Product Information
Name:HDAC8-IN-12
Brand:Targetmol
Description:HDAC8-IN-12 (compound 5k), a non-hydroxamic acid derivative, serves as a selective HDAC8 inhibitor with an IC 50 of 0.12 nM and demonstrates potent efficacy against breast cancer. This compound enhances anti-tumor immunity by activating T cells, elevating M1 macrophage levels, and reducing M2 macrophage proportions. In an orthotopic mouse model of breast cancer, HDAC8-IN-12, administered at 50 mg/kg, effectively suppresses tumor growth.
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Chemical properties
Molecular weight:331.32
Formula:C16H17N3O5
Color/Form:Solid
Technical inquiry about: HDAC8-IN-12
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