Estimated delivery in United States, on Tuesday 4 Mar 2025
Product Information
Name:
HDAC8-IN-12
Description:
HDAC8-IN-12 (compound 5k), a non-hydroxamic acid derivative, serves as a selective HDAC8 inhibitor with an IC 50 of 0.12 nM and demonstrates potent efficacy against breast cancer. This compound enhances anti-tumor immunity by activating T cells, elevating M1 macrophage levels, and reducing M2 macrophage proportions. In an orthotopic mouse model of breast cancer, HDAC8-IN-12, administered at 50 mg/kg, effectively suppresses tumor growth.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
331.32
Formula:
C16H17N3O5
Color/Form:
Liquid
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TM-T200383 HDAC8-IN-12
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