Estimated delivery in United States, on Monday 3 Mar 2025
Product Information
Name:
AJI-214
Description:
AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
357.77
Formula:
C17H13ClFN5O
Color/Form:
Liquid
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TM-T200387 AJI-214
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