Product Information
Name:AJI-214
Brand:Targetmol
Description:AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:357.77
Formula:C17H13ClFN5O
Color/Form:Solid
Technical inquiry about: AJI-214
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