DA-143
Ref. TM-T200773
Product Information
Name:DA-143
Brand:Targetmol
Description:DA-143 is a selective inhibitor of DNA-PKcs (IC50: 2.5 nM), demonstrating disparate inhibitory effects on mTOR, PI3KΔ, and ATM, with IC50 values of 280 nM, 106 nM, and 6,594 nM, respectively. This compound effectively blocks the phosphorylation of DNA-PKcs substrates and enhances the sensitivity of cancer cells to doxorubicin.
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Chemical properties
Color/Form:Odour Solid
Technical inquiry about: DA-143
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