DA-143
Ref. TM-T200773
10mg | To inquire | ||
50mg | To inquire |
Product Information
DA-143 is a selective inhibitor of DNA-PKcs (IC50: 2.5 nM), demonstrating disparate inhibitory effects on mTOR, PI3KΔ, and ATM, with IC50 values of 280 nM, 106 nM, and 6,594 nM, respectively. This compound effectively blocks the phosphorylation of DNA-PKcs substrates and enhances the sensitivity of cancer cells to doxorubicin.
Chemical properties
Technical inquiry about: TM-T200773 DA-143
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