


BCR-ABL-IN-10
Ref. TM-T200894
10mg | To inquire | ||
50mg | To inquire |
Product Information
BCR-ABL-IN-10 (compound B4) is a covalent BCR-ABL inhibitor featuring an arylvinylsulfonate (AVS) moiety, demonstrating an IC50 of 43.1 nM against ABL kinase. It forms a covalent and stable adduct with ABL kinase, enabling the sustained inhibition of intrinsic BCR-ABL activity. This compound is utilized in the study of chronic myeloid leukemia (CML).
Chemical properties
Technical inquiry about: TM-T200894 BCR-ABL-IN-10
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