


JAK/HDAC-IN-4
Ref. TM-T201233
10mg | To inquire | ||
50mg | To inquire |
Product Information
JAK/HDAC-IN-4 (compound 11 i) is a dual inhibitor targeting both JAK2 and HDAC6, with IC50 values of 0.49 nM and 12 nM respectively. It inhibits cell proliferation and the production of nitric oxide. In a mouse model induced by Imiquimod, JAK/HDAC-IN-4 ameliorates psoriasiform skin lesions with low toxicity.
Chemical properties
Technical inquiry about: TM-T201233 JAK/HDAC-IN-4
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