SIAIS562055
Ref. TM-T201329
Product Information
Name:SIAIS562055
Brand:Targetmol
Description:SIAIS562055, a potent cereblon-based SOS1PROTAC, exhibits a dissociation constant (Kd) of 95.9 nM. It effectively degrades SOS1 and inhibits the downstream ERK pathway. SIAIS562055 disrupts the interaction between KRASG12C or KRASG12D and SOS1, with IC50 values of 95.7 nM and 134.5 nM, respectively. This compound demonstrates strong anticancer activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:918.12
Formula:C49H62F3N7O5S
Color/Form:Solid
Technical inquiry about: SIAIS562055
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