Product Information
Name:Emavusertib Phosphate
Brand:Targetmol
Description:Emavusertib Phosphate (also known as CA-4948) is a potent inhibitor of IRAK4 and FLT3, exhibiting antitumor activity. In ABC DLBCL and AML cell lines, it demonstrates significant cellular efficacy. Furthermore, CA-4948 shows moderate to high selectivity across a panel of 329 kinases and possesses favorable ADME and PK profiles, including good oral bioavailability in mice, rats, and dogs. It achieves over 90% tumor growth inhibition in relevant tumor models and correlates excellently with in vivo PD modulation.
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Chemical properties
Molecular weight:589.49
Formula:C24H28N7O9P
Technical inquiry about: Emavusertib Phosphate
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