Product Information
Name:SD-436
Synonyms:
- SD436
Brand:Targetmol
Description:SD-436 is a selective and highly efficient STAT3 PROTAC degrader (DC50 = 0.5 μM), with an IC50 of 19 nM for STAT3, significantly higher than for STAT1/4/5/6. SD-436 depletes STAT3 and induces tumour regression in mouse leukaemia and lymphoma xenograft models.
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Chemical properties
Molecular weight:1248.2
Formula:C58H62F4N9O14PS
Purity:99.34%
Color/Form:Solid
Technical inquiry about: SD-436
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