SOS1-IN-17
Ref. TM-T203656
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
Product Information
Name:
SOS1-IN-17
Description:
SOS1-IN-17 (Compound 8d) is an orally active inhibitor targeting the SOS1-KRASG12C interaction, with an IC50 of 5.1 nM. It suppresses ERK phosphorylation in DLD-1 cells with an IC50 of 18 nM and demonstrates antiproliferative activity in KRASG12C-mutant Mia-Paca-2 cells, with an IC50 of 0.11 μM. In mouse models, SOS1-IN-17 shows antitumor efficacy against pancreatic cancer.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
541.61
Formula:
C29H34F3N5O2
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TM-T203656 SOS1-IN-17
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