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EGFR-IN-144

Ref. TM-T204605

EGFR-IN-144
Targetmol

Product Information

Name:EGFR-IN-144
Brand:Targetmol
Description:EGFR-IN-144 (Compound 4B) inhibits EGFR (IC50=0.639 µg/mL) and tubulin polymerization (IC50=7.339 µg/mL). It exhibits cytotoxicity in various cancer cells with a GI50 at the nanomolar level. EGFR-IN-144 reduces the expression of mTOR, TNF-α, and IL-6, causes G1/S phase cell cycle arrest, and induces apoptosis.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:418.273
Formula:C20H17Cl2N3O3
Color/Form:Solid

Technical inquiry about: EGFR-IN-144

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