JNK3 inhibitor-9
Ref. TM-T204724
Product Information
Name:JNK3 inhibitor-9
Brand:Targetmol
Description:JNK3inhibitor-9 (Compound 24a) is a potent, selective JNK3 inhibitor capable of crossing the blood-brain barrier (BBB), demonstrating an IC50 value of 12 nM. It effectively inhibits GSK3α/β, which is involved in Tau phosphorylation, with IC50 values of 14 nM and 35 nM, respectively. JNK3inhibitor-9 also reduces the phosphorylation of c-Jun and APP and protects neurons from Aβ1-42 toxicity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:457.528
Formula:C25H27N7O2
Color/Form:Solid
Technical inquiry about: JNK3 inhibitor-9
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