PROTAC BTK Degrader-13
Ref. TM-T205064
Product Information
Name:PROTAC BTK Degrader-13
Brand:Targetmol
Description:PROTAC BTK Degrader-13 (Compound 25) is a targeted BTK PROTAC degrader with a DC50 of 0.27 μM. It inhibits BTK activity with an IC50 of 0.44 μM and suppresses IL-2-induced T cell kinase (ITK) with an IC50 of 2.16 μM. This compound also inhibits the p38 MAPK signaling pathway, thereby blocking the activation of the BCR (B cell receptor) signaling pathway. [Pink: ligand for target protein BTK ligand 15; Black: linker; Blue: ligand for E3 ligase cereblon]
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:622.63
Formula:C33H30N6O7
Color/Form:Solid
Technical inquiry about: PROTAC BTK Degrader-13
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