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EP-3945

CAS:

Ref. TM-T205219

EP-3945
Targetmol

Product Information

Name:EP-3945
Brand:Targetmol
Description:EP-3945 is an agonist of Mas-related G protein-coupled receptors (MRGPR), exhibiting greater potency than the small molecule agonist β-Alanine targeting MRGPRD. MRGPRs play a crucial role in inflammatory itch and pain perception. These receptors interact with Gq (MRGPRX2, MRGPRX4, and MRGPRX1 are coupled with Gq; MRGPRX2 and MRGPRD couple with Gi), with EP-3945 having an EC50 value of 211.6 nM for Gq.
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Chemical properties

Molecular weight:418.488
Formula:C24H26N4O3
Color/Form:Solid

Technical inquiry about: EP-3945

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