Product Information
Name:M3686
Brand:Targetmol
Description:M3686 (Compound 29) is a potent and selective TEAD1 inhibitor with an IC50 value of 51 nM. It exhibits weaker binding activity toward TEAD3. M3686 significantly inhibits the cellular activity of YAP-dependent NCI-H226 cell lines, with an IC50 value of 0.06 μM, and demonstrates strong antitumor effects in the NCI-H226 xenograft model.
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Chemical properties
Molecular weight:429.395
Formula:C21H18F3N5O2
Color/Form:Solid
Technical inquiry about: M3686
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