Product Information
Name:TrxR/EGFR-IN-1
Brand:Targetmol
Description:TrxR/EGFR-IN-1 (Compound L1Au2) is a TrxR/EGFR inhibitor with activity against both gefitinib-sensitive and -resistant lung cancer, effectively suppressing tumor proliferation and promoting apoptosis. It enhances GPX4 degradation through autophagosome-lysosome and proteasome pathways, leading to ferroptosis. Additionally, it induces endoplasmic reticulum stress and triggers immunogenic cell death, making it applicable for studies on gefitinib-resistant lung cancer.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:710.878
Formula:C24H24AuClFN6O2P
Color/Form:Solid
Technical inquiry about: TrxR/EGFR-IN-1
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