SOS1-IN-18
Ref. TM-T205557
Product Information
Name:SOS1-IN-18
Brand:Targetmol
Description:SOS1-IN-18 (Compound 8) is an inhibitor of the Son of Sevenless 1 protein (SOS1) with a dissociation constant (KD) of 2.6 nM. It disrupts the SOS1-KRAS G12C interaction with an IC50 of 3.4 nM, inhibits ERK phosphorylation in H358 cells with an IC50 of 31 nM, and curtails the proliferation of H358 cells with an IC50 of 5 nM.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:486.53
Formula:C26H29F3N4O2
Color/Form:Solid
Technical inquiry about: SOS1-IN-18
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