Product Information
Name:R1-ICR-5
Brand:Targetmol
Description:R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1007.31
Formula:C54H70N8O7S2
Color/Form:Solid
Technical inquiry about: R1-ICR-5
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