Product Information
Name:NLRP3-IN-78
Brand:Targetmol
Description:NLRP3-IN-78 (compound 21) is an NLRP3 inhibitor with a 46.72% inhibition rate of GSDMD-induced pyroptosis at 5 μM. It binds to the NLRP3 protein and prevents GSDMD-NT oligomerization. Additionally, NLRP3-IN-78 inhibits GSDMD cleavage and upstream NF-κB signaling, demonstrating anti-inflammatory activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:390.222
Formula:C12H5Cl2N3O4S2
Color/Form:Solid
Technical inquiry about: NLRP3-IN-78
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