Product Information
Name:HEMTAC WEE1 degrader-1
Brand:Targetmol
Description:HEMTACWEE1degrader-1 is a WEE1-targeting heterobifunctional chimeric degrader (HEMTAC) facilitated by HSP90, exhibiting an HSP90 enzyme inhibitory activity with an IC50 of 16.76 nM. It enhances the ubiquitination and subsequent degradation of WEE1, effectively blocking the G2/M cell cycle transition. This compound shows anticancer properties in patient-derived xenograft (PDX) models of acute myeloid leukemia (AML). HEMTACWEE1degrader-1 is utilized in AML research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1062.27
Formula:C57H71N15O6
Color/Form:Solid
Technical inquiry about: HEMTAC WEE1 degrader-1
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