Antifibrotic agent 1
Ref. TM-T207178
Product Information
Name:Antifibrotic agent 1
Brand:Targetmol
Description:Antifibrotic agent 1 is an orally active medication designed to treat idiopathic pulmonary fibrosis (IPF). It effectively mitigates IPF-related processes, including TGF-β-induced epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT), as well as profibrotic M2 polarization. Antifibrotic agent 1 selectively inhibits CSF-1R, PDGFR-α, and Src family kinases (SFKs), while sparing VEGFR, FGFR, and Abl to minimize off-target toxicity. In a bleomycin (BLM)-induced pulmonary fibrosis mouse model, it demonstrates strong antifibrotic activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:498.1571
Formula:C27H23ClN6O2
Color/Form:Solid
Technical inquiry about: Antifibrotic agent 1
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