LC-SF-14
Ref. TM-T207213
Product Information
Name:LC-SF-14
Brand:Targetmol
Description:LC-SF-14 is a selective dual inhibitor of SHP2 and FGFR, with IC50 values of 71.6 nM and 8.9 nM, respectively. It blocks FGFR2-FRS2α-SHP2-MAPK signaling and ERK phosphorylation, and also inhibits the proliferation of KATOIII cancer cells (IC50: 9.2 nM). Furthermore, LC-SF-14 exhibits antitumor activity in SNU-16 xenograft mouse models, making it suitable for research on FGFR2-driven gastric cancer.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:977.28442
Formula:C44H50Cl3N13O5S
Color/Form:Solid
Technical inquiry about: LC-SF-14
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