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Mrgx2 antagonist-3

CAS:

Ref. TM-T207226

Mrgx2 antagonist-3
Targetmol

Product Information

Name:Mrgx2 antagonist-3
Brand:Targetmol
Description:Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.
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Chemical properties

Molecular weight:291.30
Formula:C15H15F2N3O
Color/Form:Solid

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