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Dopamine D4 receptor ligand 3

CAS:

Ref. TM-T207369

Dopamine D4 receptor ligand 3
Targetmol

Product Information

Name:Dopamine D4 receptor ligand 3
Brand:Targetmol
Description:Dopamine D4 receptor ligand 3 (Compound 16) functions as a dopamine D4 receptor (D4R) antagonist with a pKi of 8.86. In HEK-293T cells, it shows pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors, respectively. This compound inhibits the activity of human glioma cell lines U87 MG, T98G, and U251 MG, and it induces ROS production and mitochondrial dysfunction in these glioma cells.
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Chemical properties

Molecular weight:489.56
Formula:C28H31N3O5
Color/Form:Solid

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