LWY713
Ref. TM-T208355
10mg
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50mg
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Product Information
Name:LWY713
Brand:Targetmol
Description:LWY713 is a PROTAC-based FLT3 degrader (DC50=0.64 nM) that selectively induces FLT3 degradation through a cereblon and proteasome-dependent mechanism. It inhibits cell proliferation and causes G0/G1 phase arrest and apoptosis (apoptosis) in MV4-11 cells. In MV4-11 xenograft models, LWY713 demonstrates significant in vivo antitumor activity. The E3 ligase ligand and linker consist of Lenalidomide-Glycolic acid, while the target protein ligand's active control is NaproxenGilteritinib.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:838.41261
Formula:C43H54N10O8
Technical inquiry about: LWY713
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