ERK1/2 inhibitor 10
Ref. TM-T209644
Product Information
Name:ERK1/2 inhibitor 10
Brand:Targetmol
Description:ERK1/2 inhibitor 10 (Compound 36c) is a potent inhibitor of ERK1 and ERK2, with IC50 values of 0.11 nM and 0.08 nM, respectively. It effectively hinders the phosphorylation of downstream substrates p90RSK and c-Myc. Additionally, ERK1/2 inhibitor 10 induces apoptosis and incomplete autophagy-related cell death. This compound demonstrates significant antitumor efficacy in models of triple-negative breast cancer and colorectal cancer harboring BRAF and RAS mutations.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:465.10262
Formula:C23H20ClN5O2S
Technical inquiry about: ERK1/2 inhibitor 10
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