Trivalent hydroxyarsinothricn
Ref. TM-T210094
Product Information
Name:Trivalent hydroxyarsinothricn
Synonyms:
- R-AST-OH
Brand:Targetmol
Description:Trivalent hydroxyarsinothricn (R-AST-OH) is a covalent and irreversible inhibitor of kidney-type glutaminase (KGA). It binds to the glutamine binding site and forms a covalent bond with the cysteine residue at the active site. This compound selectively kills triple-negative breast cancer (TNBC) cells without being cytotoxic to control cell lines. KGA is an enzyme that regulates glutamine metabolism and is associated with tumor malignancy.
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Chemical properties
Molecular weight:210.98258
Formula:C4H10AsNO4
Technical inquiry about: Trivalent hydroxyarsinothricn
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