PROTAC FLT3/CDKs degrader-1
Ref. TM-T210236
Product Information
Name:PROTAC FLT3/CDKs degrader-1
Brand:Targetmol
Description:PROTACFLT3/CDKs degrader-1 (Compound C3) is an agent that degrades cyclin-dependent kinase (CDK2 with a DC50 of 18.73 nM) and FMS-like tyrosine kinase 3 (FLT3). It induces differentiation in HL-60 cells, achieving a 72.77% differentiation rate at 6.25 nM, and inhibits proliferation of acute myeloid leukemia (AML) cells, with an IC50 ranging from 2.9 to 37 nM. PROTACFLT3/CDKs degrader-1 demonstrates potential for improving the treatment of AML.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:770.34011
Formula:C40H42N12O5
Technical inquiry about: PROTAC FLT3/CDKs degrader-1
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