Product Information
Name:DeFer-2
Brand:Targetmol
Description:DeFer-2 is a ferritin PROTAC degrader (Kd= 17.1 μM). It triggers the degradation of ferritin leading to the accumulation of free iron ions and an increase in ROS, which subsequently initiates caspase 3-GSDME mediated pyroptosis in cancer cells. DeFer-2 significantly inhibits tumor growth and extends the survival of mice with subcutaneous B16F10 tumors, and it is useful for melanoma research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:780.11
Formula:C44H69N5O5S
Color/Form:Solid
Technical inquiry about: DeFer-2
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.