Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 178 products for "Caspase".
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Diclofenac sodium
CAS:Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.Formula:C14H10Cl2NNaO2Purity:98.21% - 99.92%Color and Shape:SolidMolecular weight:318.13ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formula:C15H18Cl2N2O2SPurity:99.69%Color and Shape:SolidMolecular weight:361.29Diclofenac diethylamine
CAS:Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).Formula:C18H22Cl2N2O2Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:369.29Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:SolidMolecular weight:180.1574Diclofenac
CAS:Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.Formula:C14H11Cl2NO2Purity:99.69% - 99.99%Color and Shape:White SolidMolecular weight:296.149Inclisiran sodium
CAS:Inclisiran (ALN-PCSsc) possesses antihypertensive activity, inhibiting the transcription of PCSK9, and can be used to research cardiovascular diseases.Purity:99.29%Color and Shape:Odour SolidAc-FLTD-CMK
CAS:Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.Formula:C26H37ClN4O8Purity:98.61%Color and Shape:SolidMolecular weight:569.047Ac-YVAD-CMK
CAS:Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.Formula:C24H33ClN4O8Purity:97.08% - 99.90%Color and Shape:White SolidMolecular weight:540.994Q-VD-OPH
CAS:Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.Formula:C26H25F2N3O6Purity:97.8% - 99.96%Color and Shape:SolidMolecular weight:513.49Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Formula:C27H44O7Purity:99.06% - 99.67%Color and Shape:White SolidMolecular weight:480.6341Thiabendazole
CAS:Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.Formula:C10H7N3SPurity:99.14%Color and Shape:White SolidMolecular weight:201.248Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Formula:C16H14O3Purity:98.35% - 98.74%Color and Shape:White SolidMolecular weight:254.2806Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Formula:C26H33NO6Purity:99.98%Color and Shape:White-To-Off-White Crystalline SolidMolecular weight:455.54Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.883Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.97%Color and Shape:SolidMolecular weight:471.67Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:98.34% - 99.85%Color and Shape:White SolidMolecular weight:205.639Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purity:98.59% - 99.88%Color and Shape:Brown SolidMolecular weight:250.09Ac-VDVAD-CHO TFA
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.Color and Shape:Odour SolidNEK7 degrader-1
CAS:NEK7 degrader-1 is a molecular glue degrader (DC₅₀ = 0.1 nM) that inhibits caspase-1 and IL-1β release.Formula:C21H22Cl2N4O3Purity:97.02%Molecular weight:449.33HDAC3 degrader-1
HDAC3degrader-1 (Compound Z8) is a selective HDAC3 degrader with a DC50 of 2.42 μM. It shows minimal impact on HDAC1, HDAC2, and HDAC6. By inhibiting the activation of the NLRP3 inflammasome, HDAC3degrader-1 reduces the secretion of IL-1β and caspase-1. It demonstrates significant efficacy in models of septic shock and colitis, making it valuable for anti-inflammatory research.
