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HI042

CAS:

Ref. TM-T212451

HI042
Targetmol

Product Information

Name:HI042
Brand:Targetmol
Description:HI042 is an FMS-like tyrosine kinase 3 (FLT3) inhibitor, showing an IC50 value of 0.62 μM for MOLM-13 cells, 0.33 μM for MV4-11 cells, and 0.89 μM for OCI-AML3 cells. It selectively reduces the survival rate of FLT3-internal tandem duplication (FLT3-ITD) positive cell lines, induces apoptosis, disrupts cell cycle progression, and diminishes colony-forming ability. HI042 is applicable for acute myeloid leukemia (AML) research.
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Chemical properties

Molecular weight:301.32
Formula:C14H11N3O3S
Color/Form:Solid

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