KOR agonist 6
Ref. TM-T212523
10mg
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50mg
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Product Information
Name:KOR agonist 6
Brand:Targetmol
Description:KOR agonist 6 is a KOR agonist with a Ki value of 0.25 pM. In CHO cells, it exhibits agonistic activity on MOR and DOR and inhibits forskolin-stimulated cAMP accumulation. The compound stimulates KOR-mediated [35S]GTPγS binding in HEK293 cells expressing KOR and effectively suppresses cAMP accumulation as a potent agonist, showing lower β-arrestin recruitment efficacy. Additionally, KOR agonist 6 demonstrates analgesic effects in mice and can be employed in the study of analgesics with reduced central nervous system (CNS) side effects.
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Chemical properties
Color/Form:Odour Solid
Technical inquiry about: KOR agonist 6
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