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HDAC3 degrader-1

Ref. TM-T214414

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Targetmol

Product Information

Name:HDAC3 degrader-1
Brand:Targetmol
Description:HDAC3degrader-1 (Compound Z8) is a selective HDAC3 degrader with a DC50 of 2.42 μM. It shows minimal impact on HDAC1, HDAC2, and HDAC6. By inhibiting the activation of the NLRP3 inflammasome, HDAC3degrader-1 reduces the secretion of IL-1β and caspase-1. It demonstrates significant efficacy in models of septic shock and colitis, making it valuable for anti-inflammatory research.
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Chemical properties

Technical inquiry about: HDAC3 degrader-1

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