Lb54
Ref. TM-T217974
Product Information
Name:Lb54
Brand:Targetmol
Description:Lb54 is an activator of caspase-3 and caspase-7 with an EC50 of 660.9 nM for human procaspase-3. It activates caspase-3/7, which cleaves Gasdermin D (GSDMD) at the aspartic acid residue 87 to produce a p10 fragment, thus preventing the formation of the pore-forming p30 fragment of GSDMD. By activating caspase-3/7, Lb54 inhibits GSDMD-mediated pyroptosis, thereby reducing inflammation and providing protection against sepsis. Additionally, Lb54 alleviates acute lung injury and suppresses systemic inflammation by inhibiting the maturation of monocyte-derived dendritic cells. Lb54 is applicable in sepsis-related research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Technical inquiry about: Lb54
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please add the desired products to your cart and manage the request from there. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.