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Bimiralisib
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Bimiralisib

CAS: 1225037-39-7

Ref. TM-T2265

1mg
42.00 €
2mg
56.00 €
5mg
89.00 €
10mg
120.00 €
25mg
216.00 €
50mg
364.00 €
100mg
548.00 €
500mg
1,194.00 €
Estimated delivery in United States, on Wednesday 17 Apr 2024

Product Information

Name:
Bimiralisib
Synonyms:
  • 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine, PQR309, PI3K-IN-2
Description:

Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
411.38
Formula:
C17H20F3N7O2
Purity:
99.88%
Color/Form:
Solid
InChI:
InChI=1S/C17H20F3N7O2/c18-17(19,20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H,1-8H2,(H2,21,22)
InChI key:
InChIKey=ADGGYDAFIHSYFI-UHFFFAOYSA-N
SMILES:
Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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