Surfen dihydrochloride

CAS: 5424-37-3

Ref. TM-T26240

Product Information

• Name: Surfen dihydrochloride
• Synonyms: Aminokinuride dihydrochloride, Aminoquinuride dihydrochloride, NSC-12155, Aminokinuride 2HCl, Aminoquinuride 2HCl, 1,3-Bis(4-Amino-2-Methylquinolin-6-Yl)Urea Dihydrochloride, 1,3-Bis(4-amino-2-methyl0-6-chinolyl)urea dihydrochlorid, Aminoquincarbamide dihydrochloride, Aminoquinurid dihydrochlorid, Aminoquinuride HCl, Aminoquinuride dihydrochloride, Bis-(2-methyl-4-amino-6-quinolyl)carbamide dihydrochloride, Nsc 12155, Unii-P2Yt71Suiu, Urea, 1,3-bis(4-amino-2-methyl-6-quinolyl)-, dihydrochloride, Urea, N,N'-bis(4-amino-2-methyl-6-quinolinyl)-, dihydrochloride (9CI), Urea, N,N′-bis(4-amino-2-methyl-6-quinolinyl)-, dihydrochloride, Urea, N,N′-bis(4-amino-2-methyl-6-quinolinyl)-, hydrochloride (1:2)
• CAS: 5424-37-3

Description

Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and lethal factor.Surfen inhibits the anticoagulant activity of both normal and low-molecular-weight heparin and inhibits heparin sulfation and heparin cleavage enzyme degradation.Surfen inhibits the blockade of FGF2 binding and signaling mediated by heparin acetylsulfate. Surfen inhibits the blockade of acetylheparin sulfate-mediated FGF2 binding and signaling.Surfen inhibits SEVI and semen-mediated enhancement of HIV type 1 infection.

• Brand: Targetmol

Chemical properties

• Molecular weight: 445.35
• Formula: C₂₁H₂₂Cl₂N₆O
• Purity: 97.08%
• Color/Form: Solid