Triparanol

CAS: 78-41-1

Ref. TM-T26296

Product Information

• Name: Triparanol
• Synonyms: MER-29, NSC 65345, NSC-65345, NSC65345, 1-(4-(2-(Diethylamino)ethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol, 1-(p-(beta-Diethylaminoethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol, 1-[p-(β-Diethylaminoethoxy)phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol, 2-(4-Chlorophenyl)-1-{4-[2-(Diethylamino)Ethoxy]Phenyl}-1-(4-Methylphenyl)Ethanol, 2-(p-Chlorophenyl)-1-(p-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)ethanol, 2-(p-Chlorophenyl)-1-[p-(β-diethylaminoethoxy)phenyl]-1-(p-tolyl)ethanol, 2-p-Chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol, 4-Chloro-α-[4-[2-(diethylamino)ethoxy]phenyl]-α-(4-methylphenyl)benzeneethanol, Acosterina, Benzeneethanol, 4-chloro-alpha-(4-(2-(diethylamino)ethoxy)phenyl)-alpha-(4-methylphenyl)- (9CI), Benzeneethanol, 4-chloro-α-[4-[2-(diethylamino)ethoxy]phenyl]-α-(4-methylphenyl)-, Brn 2064866, Clotrox, Diticyl, Drenaren, Ethanol, 2-(p-chlorophenyl)-1-(p-(2-(diethylamino)ethoxy)phenyl)-1-p-tolyl-, Hipocolestina, MER 2p, Mer 29, Metasclene, Metasqualene, Nsc 65345, Sclane, Trianel, Trikosterol, Triparanol [INN:BAN], Triparanolo, Triparanolo [DCIT], Triparanolum, Triparanolum [INN-Latin], Triparin, Tropalin, Valip, Verdiana, alpha-(p-Chlorobenzyl)-4-diethylaminoethoxy-4'-methylbenzhydrol
• CAS: 78-41-1

Description

Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.

• Brand: Targetmol

Chemical properties

• Molecular weight: 438
• Formula: C₂₇H₃₂ClNO₂
• Purity: 99.73%
• Color/Form: Solid