Cobimetinib
CAS: 934660-93-2
Ref. TM-T3623
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 445.00 € | ||
| 500mg | To inquire | ||
| 1ml*10 (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 15 May 2024
Product Information
Name:
Cobimetinib
Synonyms:
- RG7420, XL518, GDC-0973
- (S)-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone
- Gdc-0973
- Methanone, [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]-
- Rg 7421
- Rg7421
- Xl 518
- [3,4-Difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone
- [3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]methanone
CAS:
Description:
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) phosphorylation and activation and decreased tumor cell proliferation.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
531.31
Formula:
C21H21F3IN3O2
Purity:
100%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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