MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Found 75 products for "MEK".
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PD 198306
CAS:PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Formula:C18H16F3IN2O2Purity:99.66%Color and Shape:SolidMolecular weight:476.23Ref: TM-T21980
1mg60.00€5mg131.00€1mL*10mM (DMSO)152.00€10mg178.00€25mg314.00€50mg447.00€100mg622.00€500mg1,224.00€Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurity:99.88% - >99.99%Color and Shape:White SolidMolecular weight:234.34Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurity:99.95%Color and Shape:SolidMolecular weight:288.82Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurity:99.83% - 99.92%Color and Shape:SolidMolecular weight:270.798Cobimetinib (R-enantiomer)
CAS:Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.Formula:C21H21F3IN3O2Purity:98%Color and Shape:SolidMolecular weight:531.318MAPK Inhibitor Library
A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L1400
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireLuvometinib-d
Luvometinib-d is a deuterium-labeled version of Luvometinib, which is a mitogen-activated protein kinase (MEK) inhibitor with antitumor properties.MEK1/2-IN-3
MEK1/2-IN-3 (Compound M15) is an inhibitor of MEK1, with an IC50 value of 10.29 nM. It effectively suppresses tumor cell proliferation and migration, induces apoptosis, and exhibits good liver microsomal stability. MEK1/2-IN-3 is applicable in the study of solid tumors.Formula:C28H23F3IN3O4Color and Shape:SolidMolecular weight:649.4MEK4 inhibitor-1
CAS:MEK4 inhibitor-1 targets MEK4 enzyme in pancreatic cancer, IC50=61 nM.Formula:C13H10FN3O2SColor and Shape:SolidMolecular weight:291.3MS432
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.Formula:C50H65F3IN7O6SPurity:98%Color and Shape:SolidMolecular weight:1076.06U0124
CAS:Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative controlFormula:C8H10N4S2Purity:98%Color and Shape:SolidMolecular weight:226.32FDA-Approved Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Color and Shape:LiquidRef: TM-L1610
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireNST-628
CAS:NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK. NST-628 inhibits the RAF-MEK signaling complex.Formula:C22H18F2N4O5SPurity:98.62% - 98.86%Color and Shape:White SolidMolecular weight:488.46Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asColor and Shape:Lyophilized PowderMolecular weight:16.46 kDa (predicted) same as Tris-Bis PAGE result.Ref: TM-TMPK-00024
5µg94.00€10µg138.00€20µg220.00€50µg434.00€100µg732.00€200µg1,324.00€500µg2,925.00€Midkine Protein, Human, Recombinant (His & Avi)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asPurity:> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGEColor and Shape:White Lyophilized PowderMolecular weight:16.46 kDa (predicted) same as Tris-Bis PAGE result.Anti-Midkine Antibody (5T766)
Anti-Midkine Antibody (5T766) is an antibody targeting Midkine. Anti-Midkine Antibody (5T766) can be used in ELISA, IHC.Color and Shape:Odour LiquidMidkine Protein, Mouse, Recombinant (His)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asPurity:> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCColor and Shape:Transparent SolutionMolecular weight:14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.Refametinib
CAS:Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).Formula:C19H20F3IN2O5SPurity:99.85% - >99.99%Color and Shape:SolidMolecular weight:572.34Ref: TM-T6636
2mg43.00€5mg63.00€1mL*10mM (DMSO)79.00€10mg93.00€25mg147.00€50mg222.00€100mg326.00€200mg485.00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Green SolidMolecular weight:267.28Ref: TM-T2623
5mg38.00€1mL*10mM (DMSO)39.00€10mg50.00€25mg78.00€50mg101.00€100mg168.00€200mg250.00€500mg421.00€BIX02189
CAS:BIX 02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).Formula:C27H28N4O2Purity:97.84%Color and Shape:SolidMolecular weight:440.54Ref: TM-T21295
2mg33.00€5mg52.00€1mL*10mM (DMSO)55.00€10mg71.00€25mg119.00€50mg198.00€100mg296.00€200mg427.00€
