Pirtobrutinib
CAS: 2101700-15-4
Ref. TM-T36287
1mg | 37.00 € | ||
5mg | 78.00 € | ||
10mg | 123.00 € | ||
25mg | 278.00 € | ||
50mg | 425.00 € | ||
100mg | 628.00 € | ||
500mg | 1,336.00 € | ||
1ml*10 (DMSO) | 82.00 € |
Product Information
- LOXO-305
Pirtobrutinib (LOXO-305) is an advanced BTK inhibitor that displays high selectivity and operates through a non-covalent mechanism. This compound effectively inhibits various BTK C481 substitution mutations, leading to tumor regression in BTK-dependent lymphoma tumors in mouse xenograft models. Furthermore, Pirtobrutinib exhibits remarkable selectivity for BTK, with more than a 300-fold difference compared to 370 other kinases tested. Notably, at a concentration of 1 μM, Pirtobrutinib demonstrates no significant inhibition of non-kinase off-targets.
Chemical properties
Technical inquiry about: TM-T36287 Pirtobrutinib
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