(S)-Coriolic acid
CAS: 29623-28-7
Ref. TM-T37974
| 1mg | 681.00 € | ||
| 5mg | 1,291.00 € | ||
| 100µg | 140.00 € | ||
| 250µg | 303.00 € | ||
| 500µg | 457.00 € |
Product Information
- 13(S)-HODE
(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid inhibits the adhesion of tumor cells to the vascular endothelium and down-regulates the expression of IRGpIIb/IIIa receptors at around 1 μM. (S)-Coriolic acid is a metabolite of 15-lipoxygenase (15-LOX), which often acts as an endogenous ligand to activate PPARγ. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial damage.
Chemical properties
Technical inquiry about: TM-T37974 (S)-Coriolic acid
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