Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 131 products for "Lipoxygenase".
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Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.86%Color and Shape:White SolidMolecular weight:236.29ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.Formula:C15H18N2OSPurity:99.98%Color and Shape:SolidMolecular weight:274.38Ref: TM-T67908
5mg34.00€1mL*10mM (DMSO)44.00€10mg50.00€25mg100.00€50mg166.00€100mg279.00€200mg398.00€Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Color and Shape:SolidMolecular weight:404.419DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurity:97.08%Color and Shape:SoildMolecular weight:194.2613-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SColor and Shape:SolidMolecular weight:446.1260115-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Color and Shape:SolidMolecular weight:412.87CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purity:99.93%Color and Shape:SoildMolecular weight:247.72CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purity:98%Color and Shape:SolidMolecular weight:322.331-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purity:99.79%Color and Shape:SolidMolecular weight:338.27Ref: TM-T21838
5mg54.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg161.00€50mg245.00€100mg346.00€200mg474.00€ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.445-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColor and Shape:SolidMolecular weight:365.82E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:White SolidMolecular weight:413.94Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Color and Shape:SolidMolecular weight:355.39(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.505BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColor and Shape:White SolidMolecular weight:308.52Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.42KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurity:99.44%Color and Shape:SolidMolecular weight:266.36Ref: TM-T77288
2mg34.00€5mg52.00€1mL*10mM (DMSO)55.00€10mg79.00€25mg119.00€50mg187.00€100mg314.00€200mg447.00€5-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.42
