Cucurbitacin IIA

CAS: 58546-34-2

Ref. TM-T3S1471

Product Information

• Name: Cucurbitacin IIA
• Synonyms: Dihydrocucurbitacin Q1, Hemslecin A, Curcurbitacin IIA, (2β,3α,9β,10α,16α)-25-(Acetyloxy)-2,3,16,20-tetrahydroxy-9-methyl-19-norlanost-5-ene-11,22-dione, 19-Norlanost-5-ene-11,22-dione, 25-(acetyloxy)-2,3,16,20-tetrahydroxy-9-methyl-, (2beta,3alpha,9beta,10alpha,16alpha)-, 19-Norlanost-5-ene-11,22-dione, 25-(acetyloxy)-2,3,16,20-tetrahydroxy-9-methyl-, (2β,3α,9β,10α,16α)-, 23,24-Dihydrocucurbitacin F 25-acetate, 23,24-Dihydrocucurbitacin F-25-O-acetate, 25-Acetoxy-23,24-dihydrocucurbitacin F, 25-O-Acetyl-23,24-dihydrocucurbitacin F, Cucurbitacin II_a, Dihydrocucurbitacin F 25-O-acetate, Dihydrocucurbitacin Q1, Hemslecin A, estr-5-en-11-one, 17-[(1R)-5-(acetyloxy)-1-hydroxy-1,5-dimethyl-2-oxohexyl]-2,3,16-trihydroxy-4,4,9,14-tetramethyl-, (2beta,3alpha,9beta,10alpha,16alpha,17beta)-
• CAS: 58546-34-2

Description

1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.

• Brand: Targetmol

Chemical properties

• Molecular weight: 562.73
• Formula: C₃₂H₅₀O₈
• Purity: 99.87%
• Color/Form: Solid