RO1138452
CAS: 221529-58-4
Ref. TM-T4436
| 1mg | 52.00 € | ||
| 2mg | 68.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 791.00 € | ||
| 1ml*10 (DMSO) | 94.00 € |
Product Information
- CAY10441
- Cay 10441
- Ro 1138452
RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 1.5 nM. At levels between 2-20 mg/kg in rats, CAY10441 shows significant analgesic activity in standard antinociceptive assays [1].
Chemical properties
Technical inquiry about: TM-T4436 RO1138452
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