Product Information
Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor that prevents MRN-dependent activation of ATM (IC50 =12 μM) without affecting ATM protein kinase activity, and inhibits Mre11-associated exonuclease activity. Consistent with its ability to target the MRN complex, Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells [1].
Chemical properties
Technical inquiry about: TM-T60273 Mirin
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