Product Information
- 1,3-Propanediamine N1,N3-bis[3-(ethylamino)propyl]-
- 1,3-Propanediamine, N,N′-bis[3-(ethylamino)propyl]-
- 1,3-Propanediamine, N<sup>1</sup>,N<sup>3</sup>-bis[3-(ethylamino)propyl]-
- Be 3-3-3
- Be 333
- Be3-3-3
- Benspm
- De 333
- De333
- Denspm
- See more synonyms
- Diethyl-norspermine
- Diethylnorspermine
- N(1),N(11)-Diethylnorspermine
- N(Sup1),N(Sup11)-Bis(Ethyl)Norspermine
- N(Sup1),N(Sup11)-Diethylnorspermine
- N,N'-Bis(3-(Ethylamino)Propyl)-3-Propanediamine
- N<sup>1</sup>,N<sup>11</sup>-Bis(ethyl)norspermine
- N<sup>1</sup>,N<sup>11</sup>-Diethylnorspermine
- N<sup>1</sup>,N<sup>3</sup>-Bis[3-(ethylamino)propyl]-1,3-propanediamine
- N~1~,N~1~'-propane-1,3-diylbis(N~3~-ethylpropane-1,3-diamine)
N1,N11-Diethylnorspermine (DENSPM), a spermine analog, serves as a potent anticancer agent by activating polyamine catabolism, which in turn triggers cytochrome c release from mitochondria and activates caspase 3. This process ultimately leads to the death of glioblastoma multiforme (GBM) cells by inducing spermidine/spermine N1-acetyltransferase (SSAT) activity along with the production of H2O2 [1] [2] [3].
Chemical properties
Technical inquiry about: TM-T60348 N1,N11-Diethylnorspermine
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