Ro 31-8220 Mesylate

CAS: 138489-18-6

Ref. TM-T6643

Product Information

• Name: Ro 31-8220 Mesylate
• Synonyms: Ro 31-8220 methanesulfonate, Bisindolylmaleimide IX mesylate, Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1), Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, monomethanesulfonate, Methanesulfonic acid 3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl carbamimidothioate, Ro 31-8220 mesylate, Ro31-8220

Description

Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.

• Brand: Targetmol

Chemical properties

• Molecular weight: 553.65
• Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S
• Purity: 99.02% - 99.18%
• Color/Form: Solid
• InChI: InChI=1S/C25H23N5O2S.CH4O3S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20;1-5(2,3)4/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32);1H3,(H,2,3,4)
• InChI key: InChIKey=SAWVGDJBSPLRRB-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)O.Cn1cc(C2=C(c3cn(CCCSC(=N)N)c4ccccc34)C(=O)NC2=O)c2ccccc21