JNK
JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.
Found 104 products for "JNK".
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NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formula:C12H15N3O4SPurity:97.38%Color and Shape:SolidMolecular weight:297.33Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormula:C13H8O3Purity:99.45%Color and Shape:SolidMolecular weight:212.2Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formula:C11H12Cl2N2O5Purity:99.6% - 99.90%Color and Shape:White SolidMolecular weight:323.13SU3327
CAS:SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).Formula:C5H3N5O2S3Purity:98.39%Color and Shape:SolidMolecular weight:261.3Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurity:99.89%Color and Shape:SolidMolecular weight:378.31Ref: TM-T0860L
1mg66.00€5mg145.00€1mL*10mM (DMSO)152.00€10mg213.00€25mg356.00€50mg510.00€100mg715.00€200mg964.00€Tanzisertib
CAS:Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Formula:C21H23F3N6O2Purity:98.66% - 99.28%Color and Shape:SolidMolecular weight:448.44Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.99%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77JNK-IN-13
CAS:JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
Formula:C13H7ClN4SPurity:98.74%Color and Shape:SolidMolecular weight:286.74JTP10-△-TATi TFA
JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.Formula:C120H213F3N48O28Purity:98%Color and Shape:SolidMolecular weight:2833.28L-JNKI-1
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.Formula:C164H286N66O40Purity:98%Color and Shape:SolidMolecular weight:3822.44D-JBD19
CAS:D-JBD19 is a non-permeable peptide with neuroprotective effects.Formula:C99H164N32O28Purity:98%Color and Shape:SolidMolecular weight:2250.597JNK-IN-18
JNK-IN-18 (compound 23b) is a potent inhibitor of JNK1, boasting an IC50 of 2 nM. It demonstrates superior efficacy when compared to its IC50 values of 125 nM for JNK2 and 98 nM for BRAF(V600E).Color and Shape:Odour SolidD-JNKI-1
CAS:D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.Formula:C164H286N66O40Purity:98%Color and Shape:SolidMolecular weight:3822.44JNK3 inhibitor-7
Potent, oral JNK3 inhibitor-7 crosses blood-brain barrier, IC50: 53 nM (JNK3), offers neuroprotection, potential in AD research.Formula:C32H31N7O3Color and Shape:SolidMolecular weight:561.63JIP-1(153-163)
CAS:Peptide based on JIP-1(153-163) inhibits JNK with micromolar affinity; barely affects p38, ERK.Formula:C61H104N20O14Purity:98%Color and Shape:SolidMolecular weight:1341.6OVA-E1 peptide
CAS:OVA-E1 peptide, as SIINFEKL variant, triggers similar p38/JNK activation in mutant and normal thymocytes.Formula:C47H76N10O14Color and Shape:SolidMolecular weight:1005.181Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireMAPK Inhibitor Library
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;Color and Shape:Odour SolidRef: TM-L1400
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireJNK-IN-15, Cell-Permeable, Negative Control
JNK-IN-15, Cell-Permeable, Negative Control serves as the negative control for JNK-IN-15, Cell-Permeable. JNK-IN-15, Cell-Permeable functions as an inhibitor of JNK.Formula:C191H336N70O48SColor and Shape:SolidMolecular weight:4410.57236JNK3 inhibitor-8
JNK3 inhibitor-8: potent, selective, oral, BBB-penetrating, IC50: JNK3=21 nM, JNK2=2203 nM, JNK1>10,000 nM; potential in Alzheimer's research.Formula:C32H30FN7O3Color and Shape:SolidMolecular weight:579.62
